Single IRB (sIRB) Use and Administration

This course covers relying on a sIRB, serving as a sIRB of record, and authorization agreements.

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About this Course

The Single IRB (sIRB) Use and Administration course is intended for institutions relying on external IRBs and for sIRBs for multi-site research (including IRB administrators, researchers, and IRB members). It explores key considerations on external sIRB reliance, setting up and serving as a sIRB, and best practices for drafting, reviewing, and implementing authorization agreements between the sIRB and participating sites in multi-site research.

This course covers the National Institutes of Health (NIH) policy “Use of a Single Institutional Review Board for Multi-Site Research,” and the revised Common Rule (2018 Rule) cooperative research requirement.

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Language Availability: English

Suggested Audiences: Human Subject Protection Staff, Institutional Review Boards (IRBs), Institutional/Signatory Officials, IRB Administrators, IRB Administrators and Staff, IRB Chairs, Research Team Members, Researchers, Students

Organizational Subscription Price: Included with Human Subjects Research series, available as part of an organizational subscription package or for $1,000 as an add-on to current subscriptions.
Independent Learner Price: $29 per person

Demo Instructions


Course Content

Single Institutional Review Board (sIRB) Use and Administration: When Relying on a sIRB

Explores key considerations when implementing sIRB relationships and what a participating site needs to do in preparation for relying on an external sIRB.

Recommended Use: Elective
ID (Language): 17387 (English)
Author(s): James Riddle, MCSE, CIP, CPIA - Advarra; Raffaella Hart, MSHS, CIP - BRANY IRB

Single Institutional Review Board (sIRB) Use and Administration: When Serving as a sIRB of Record

Discusses key elements and considerations for setting up an IRB to serve as a sIRB.

Recommended Use: Elective
ID (Language): 17388 (English)
Author(s): James Riddle, MCSE, CIP, CPIA - Advarra; Raffaella Hart, MSHS, CIP - BRANY IRB

Single Institutional Review Board (sIRB) Use and Administration: Authorization Agreements

Introduces best practices for drafting, reviewing, and implementing authorization agreements between the sIRB and participating sites in multi-site research.

Recommended Use: Elective
ID (Language): 17392 (English)
Author(s): Cindy Gates, JD, RN, CIP - University of Miami


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