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Working with the IACUC

This course provides basic training on the protection of animal subjects used in research.

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About this Course


Working with the IACUC is intended for laboratory research personnel who will write animal-use protocols for review by an Institutional Animal Care and Use Committee (IACUC) member or who will handle animals under such protocols. It provides basic information regarding the U.S. regulations for protection of animal subjects used in research, teaching, and testing. It also describes the sources and applicability of regulations governing animals in these uses.

In addition, it discusses the role, authority, and composition of the IACUC, the types of IACUC review, and the items of information required for the review. It discusses animal surgery, blood sample collection, antibody production, and euthanasia.

General discussions are also provided for requirements for personnel training and experience, and occupational health and safety. Recommendations for housing rodents, exercising dogs, enriching the environment of primates, and using human patient care areas for animal procedures. Finally, there is a discussion of the requirements for making changes in a project involving animals and the procedures for reporting inappropriate use of animals.

Disponibilidad del idioma: English

Audiencias sugeridas: Animal Workers and Staff, IACUC Members, Investigators, Research Assistants, Students

Organizational Subscription Price: Included in organizational subscription
Independent Learner Price: $110 per person


Course Content


Working with the IACUC: Introduction New Content

Introduces the Working with the IACUC course and provides the course objectives.

Uso recomendado: Required
ID (Idioma): 17660 (English)

About the IACUC New Content

Describes basic elements, roles and responsibilities, and functions of an IACUC.

Uso recomendado: Required
ID (Idioma): 17661 (English)

Federal Laws, Policies, and Guidelines New Content

Discusses basic laws, policies, and guidelines that govern the use of animals for research, testing, and education in the United States.

Uso recomendado: Required
ID (Idioma): 17662 (English)

Planning Research and Completing the Protocol Form New Content

Explains how investigators need to complete and justify answers to items on the animal protocol form. Covers key elements of planning research including recognizing the need to consult with the veterinarian, considering alternatives to minimize animal use and pain or distress, avoiding unnecessary duplication of previous animal studies, correctly classifying procedures performed on animals into the USDA pain/distress categories, understanding the guidelines for prolonged restraint, recognizing the need for humane endpoint criteria, and understanding appropriate euthanasia methods.

Uso recomendado: Required
ID (Idioma): 17663 (English)

Procedures: Surgery, Antibody Production, and Blood Collection New Content

Covers key procedures in animal protocol forms including surgery, antibody production, and blood sample collection.

Uso recomendado: Required
ID (Idioma): 17664 (English)

Personnel and Their Welfare New Content

Discusses the importance of training for personnel involved in animal research, requirements for performing work in animals involving recombinant DNA or infectious agents, considerations that should be given when using human clinical areas for animal research, and the importance of an organizational Occupational Health and Safety Program in protecting the safety of personnel and animals.

Uso recomendado: Required
ID (Idioma): 17665 (English)

Special Animal Welfare Considerations New Content

Explains the need to house social animals in pairs or groups, and the need to justify single housing when not possible. Covers the need to preferentially house domesticated rodents in solid bottom cages with contact bedding and the requirements for organizations to establish programs for dog exercise and primate psychological enrichment.

Uso recomendado: Required
ID (Idioma): 17666 (English)

Making Changes to an Approved Animal Use Protocol New Content

Discusses the requirement and methods for obtaining IACUC approval prior to making significant changes in animal procedures, as well as other processes organizations may establish for review and approval of changes that may be more minor in nature.

Uso recomendado: Required
ID (Idioma): 17667 (English)

Reporting Animal Use Concerns New Content

Discusses the procedures for reporting misuse or mistreatment of animals or noncompliance in keeping with federal and organizational regulations, laws, policies, or guidelines.

Uso recomendado: Required
ID (Idioma): 17668 (English)


Additional Modules of Interest


Aseptic Surgery

Discusses the principles of aseptic technique with an emphasis on the practical application of these principles in the laboratory setting.

Uso recomendado: Supplemental
ID (Idioma): 12840 (English)

Antibody Production in Animals

Describes the use of antigens and adjuvants, for the production of polyclonal antibodies, and their ability to produce pain and distress. It also discusses the procedures for immunization, as well as the production of monoclonal antibodies and the use of ascites collection.

Uso recomendado: Supplemental
ID (Idioma): 13325 (English)